WEIGHT MANAGEMENT at Optimize 360


Medical Weight Loss: A Bridge to Sustainable Health

At Optimize 360, our goal is clear: utilize GLP-1 therapies to achieve your target weight, establish lasting habits, and eventually transition you off the medication. We view these treatments as a powerful metabolic tool—not a permanent crutch. Our approach combines evidence-based practice with functional health guidelines to shed weight, while you build the lifestyle necessary to keep the weight off for good.

Data-Driven Safety & Precision Safety is our priority. We validate every protocol with a thorough analysis of your Hemoglobin A1c, Fasting Insulin, and a Comprehensive Metabolic Panel (CMP). These labs allow us to establish a safe baseline and tailor the treatment to your specific metabolic needs.

Comprehensive Support & Complimentary Nutrition Plans: Medication creates the opportunity for change; habits sustain it. Our structured monthly programs include complimentary nutrition plans designed to fuel your body and maximize fat loss. Through consistent medical oversight and nutritional guidance, we help you solidify the behavioral changes required to maintain your results long after the prescription ends.

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Achieve a Healthier Weight with Expert Guidance


Semaglutide

Semaglutide is a GLP-1 receptor agonist with 94% sequence homology to native human GLP-1. It promotes weight loss through multiple mechanisms: reducing appetite and food intake via central nervous system effects, slowing gastric emptying, and improving glycemic control through glucose-dependent insulin secretion. The extended half-life of approximately 7 days is due to albumin binding and resistance to DPP-4 degradation, enabling convenient once-weekly dosing.

It works in two main ways:

  1. It Slows Your Stomach: It physically slows down how fast food leaves your stomach. You feel full much faster, and you stay full much longer. You might eat half a sandwich and genuinely feel like you just ate a Thanksgiving feast.
  2. It Balances Blood Sugar: It prevents those massive sugar spikes and crashes that usually lead to "hangry" snacking in the afternoon.
  • Pricing
  • Dosage
  • Side Effects
Pricing

Monthly Subscription:


Tier 1: $198 - .25mg - 1mg

Tier 2: $272 - 1.25mg - 1.5mg

Tier 3: $284 - 1.75mg - 2.5mg

Dosage

You cannot rush this. This medication builds up in your system. If you take too much too soon, you will feel very sick. Optimize 360 works closely with each patient to ensure gut tolerance and avoiding side effects as much as possible. 

  • The Dosage: Dosage will depends on your history of use. If you’ve never used it, we’ll start slow to build the GLP up in your system and titrate gradually over a few weeks. If you’re transferring to Optimize, we’ll evaluate your journey and make recommendations from there.
  • Goal: Support chronic weight management through GLP-1 receptor activation, leading to reduced appetite and improved metabolic parameters[1].
  • Schedule: Weekly subcutaneous injections for 16–20+ weeks with gradual dose escalation.
  • Dose Range: 250 mcg (0.25 mg) to 2400 mcg (2.4 mg) weekly with stepwise titration every 4 weeks to improve tolerability.
  • Storage: Keep refrigerated at 2–8 °C (35.6–46.4 °F); use within 28 days; avoid repeated freeze–thaw cycles.
Side Effects
  • Gastrointestinal effects (most common): nausea, vomiting, diarrhea, constipation, abdominal pain—typically mild to moderate and decreasing with gradual dose escalation[1][3].
  • Injection-site reactions: redness, swelling, or irritation (generally mild and transient)[11].
  • Hypoglycemia risk (when combined with insulin or sulfonylureas)—less common with semaglutide monotherapy due to glucose-dependent mechanism[3].
  • Rare serious adverse events: pancreatitis, gallbladder disease, acute kidney injury; thyroid C-cell tumors observed in rodent studies (relevance to humans uncertain)

Tirzepatide

If Semaglutide is the friend who gently takes the wine glass out of your hand, Tirzepatide (often sold as Mounjaro or Zepbound) is the personal trainer who reorganizes your entire kitchen while you sleep. Think of it as the "2.0 Upgrade." While the older medications hit just one "fullness button" in your brain, Tirzepatide hits two. It silences the food noise, but it also works deeper in the background to fix how your body processes sugar and fat. It’s not just about willpower anymore; it’s about giving your metabolism the instruction manual it lost somewhere in your 30s.

  • The "Double Whammy" Effect: It mimics two hormones (GLP-1 and GIP) instead of just one. This generally leads to faster and more significant weight loss than Semaglutide because it attacks hunger from two different angles.
  • Less "Morning Sickness": surprisingly, many users report fewer waves of random nausea compared to Semaglutide. The GIP hormone seems to act as a buffer, making the digestion process feel a little smoother and less like you have a stomach bug.
  • Metabolic Reset: It is exceptionally good at fixing insulin resistance. If you’ve ever felt like you gain weight just by looking at a bagel, this helps reverse that by teaching your body to use food for fuel rather than immediately storing it as fat.
  • The "Quiet" Brain: Like its predecessor, it turns off the obsessive thoughts about food, freeing up mental energy for your kids, your job, and your actual life.
  • Pricing
  • Dosage
  • Side Effects
Pricing

Monthly Subscription:


Tier 1: $360 - 2.5mg - 5mg

Tier 2: $500 - 7.5mg - 10mg

Tier 3: $700 - 12.5mg - 15mg

Dosage

Optimize 360 works very closely with our patients to ensure safe and effective use, while avoiding side effects as much as possible. We utilize slow and effective titration schedules to ensure success. Dosing will vary between patients. 

  • Goal: Support glycemic control, weight management, and metabolic health through dual incretin receptor activation[2].
  • Schedule: Weekly subcutaneous injection on the same day each week for 12–16+ weeks.
  • Dose Range: 2.5–15 mg weekly with 4week titration intervals. 
  • Storage: Keep refrigerated for up to 28 days.
Side Effects

While often better tolerated, it is still a serious medication with side effects you need to plan for.

  • Digestive "Backups": Constipation is very common. Because your digestion slows down, you need to be proactive with water and fiber, or things will come to a halt.
  • Fatigue: In the first day or two after the shot, you might feel like you need an extra nap.
  • This is your body adjusting to a lower caloric intake.
  • Burps and Indigestion: You might experience acid reflux or "sulfur burps" if you eat heavy, greasy meals. Your body will quickly teach you which foods it no longer tolerates.
  • The "Freezing" Effect: Losing fat changes your insulation, and eating less lowers your body heat. You might find yourself reaching for a sweater when everyone else is warm.

Retatrutide

While the Semaglutide and Tirzepatide work by quieting the food noise and fixing your blood sugar, Retatrutide adds a third superpower: Glucagon. This essentially turns up your body's internal thermostat, causing you to burn more calories while you sit on the couch. It is arguably the most powerful metabolic intervention ever discovered, promising results that rival bariatric surgery without the scalpel. 

  • The "Furnace" Effect: By activating the Glucagon receptor, it increases your resting energy expenditure. You aren't just eating less (like with the others); your body is actively burning more fuel just to stay alive.
  • The Liver Detox: It is shockingly effective at stripping fat out of the liver. This is a massive bonus for metabolic health, as a fatty liver is often the silent engine driving insulin resistance in middle age.
  • Unmatched Potency: In early trials, people are losing roughly 24% of their body weight in under a year. This is significantly higher than even Tirzepatide (Mounjaro).
  • Pricing
  • Dosage
  • Side Effects
Pricing

Vials start at $350

Dosage

Optimize 360 works very closely with our patients to ensure safe and effective use, while avoiding side effects as much as possible. We utilize slow and effective titration schedules to ensure success. Dosing will vary between patients.

  • Goal: Achieve substantial weight loss (up to 24% of body weight) and improved metabolic parameters through triple receptor agonism.
  • Schedule: Weekly subcutaneous injections for 12+ weeks with gradual dose escalation.
  • Dose Range: 2–12 mg once weekly;  12 mg is the maximum maintenance dose.
  • Storage: Keep solution refrigerated at 2–8 °C (35.6–46.4 °F)use within 2–4 weeks.
Side Effects

Because it turns up the "energy" in your body, the side effects are slightly different than the other two.

  • Increased Heart Rate: This is the big one. Because Glucagon is stimulating, your resting heart rate might jump up by 5–10 beats per minute. It usually settles down after a
  • few months, but it can feel like you've had an extra cup of coffee.
  • Skin Sensitivity (The "Sunburn" Feeling): About 7% of users report a strange sensation called allodynia, where the skin (usually on the back or arms) feels sensitive to the touch, almost like a mild sunburn, even though nothing is there.
  • Nausea: Like the others, it slows digestion, so if you eat too much, your stomach will punish you.

DISCLAIMER: Prescription of these medications requires a telemedicine consultation and a review of your lab results by the practitioner.

— YOUR QUESTIONS, ANSWERED

Frequently Asked Questions

What services do you offer?

Women's Health, Men's Health, Sexual Health, Testosterone Therapy, Peptide Therapy, Weight Management, and Anabolic Therapy.

Do I need a referral from my primary doctor?

No referral needed. You can book directly with us. Many of our patients come straight to Optimize 360 (even if their primary doctor dismissed their symptoms or said “your labs are normal”).

When will I see results?

Most patients feel initial improvements—like better energy, mood, and sleep—within 2–4 weeks in. Deeper changes (fat loss, stronger libido, sharper focus, full symptom relief) typically appear by 6–12 weeks. By months 3–6, the majority feel better than they have in years.


Your timeline depends on age, starting levels, and lifestyle, but we fine-tune your protocol every step so progress stays fast and steady.

How can I book a session?

Simply click the “Get Started” button and fill out the form. You’ll receive a text message to fill out your forms, schedule a consult, and even pay for labs. That’s it- once we have your info, we’ll reach out within 24 hours. No phone tag, no waiting weeks for an appointment.

How do I reorder my medications?

There's a "Refill Request" tab at the top of the website. Or text us at 765-222-9990

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