Scream Cream
A compounded topical cream designed to enhance blood flow and nerve sensitivity in women. Applied directly to the genital area before intimacy to improve arousal, sensation, and satisfaction.
Interested in Scream Cream?
Our medical team will evaluate if this medication is right for you during your consultation.
Dosage & Administration
Apply a small amount to the genital area 15-30 minutes before intimacy. Designed for local absorption with minimal systemic effects.
Important: Like any prescribed medication, dosing varies from person to person. Always follow the dosage prescribed by your healthcare provider. Optimize 360 personalizes every protocol based on your labs, symptoms, and goals.
Side Effects
Scream Cream is designed to be absorbed locally with minimal systemic side effects. Some women may experience mild tingling, warmth, or temporary sensitivity at the application site — these are expected effects, not adverse reactions.
Why Choose Optimize 360 for Scream Cream
- Prescribed and monitored by Dr. Steve Farmer — 30+ years in hormone medicine
- Comprehensive lab work before prescribing — we never guess
- Sourced from licensed U.S. compounding pharmacies
- Transparent pricing — the price above is what you pay, no hidden fees
- Telehealth available nationwide — medications shipped to your door
- Unlimited messaging with your provider throughout treatment
Get Started Today
No memberships. No referral needed. Schedule your consultation and we'll take it from there.
Related
How Scream Cream Works
Scream Cream is a compounded topical formulation designed to enhance female sexual arousal and sensitivity. It typically contains a combination of vasodilators (such as sildenafil and aminophylline), a smooth muscle relaxant (such as pentoxifylline), L-arginine (a nitric oxide precursor), and testosterone in a transdermal cream base. When applied to the clitoral and genital area, these ingredients work synergistically to increase local blood flow, enhance nerve sensitivity, and improve arousal response. The combination approach addresses multiple physiological pathways simultaneously.
Benefits & Clinical Evidence
While Scream Cream itself has not undergone large-scale randomized controlled trials as a combined formulation, its individual components are well-studied. Topical sildenafil has been shown to increase genital blood flow and arousal in women. Topical testosterone improves clitoral sensitivity and desire. L-arginine supports nitric oxide production for vasodilation. Aminophylline and pentoxifylline contribute additional vasodilatory and smooth muscle relaxant effects. Patient-reported outcomes from clinical use indicate improvements in arousal time, clitoral sensitivity, orgasm intensity, and overall sexual satisfaction.
Who Is a Good Candidate?
Scream Cream is typically prescribed for women experiencing decreased sexual arousal, reduced clitoral sensitivity, difficulty achieving orgasm, or overall decreased sexual satisfaction. These concerns are common during perimenopause and menopause, after hysterectomy, while taking certain medications (particularly SSRIs), or due to stress and hormonal changes. Women already on hormone replacement therapy may find that Scream Cream provides targeted enhancement of sexual function beyond what systemic hormones achieve. A medical evaluation is required to ensure the formulation is appropriate for you.
What to Expect: Treatment Timeline
Scream Cream is applied 15-30 minutes before sexual activity, allowing time for the ingredients to absorb and take effect. Most women notice increased warmth, tingling, and heightened sensitivity in the application area. Effects typically last 1-2 hours. Consistent use over several weeks may produce cumulative improvements in baseline arousal and sensitivity. Your provider will advise on the appropriate amount to apply — typically a small pea-sized amount to the clitoral area. Available at Optimize 360 from $131.50/bottle.
Side Effects & Safety
Common side effects include mild warmth, tingling, or temporary redness at the application site — which for many patients is actually part of the desired effect. Some women may experience sensitivity or irritation, particularly on first use. If irritation occurs, reducing the amount applied usually resolves the issue. The testosterone component is at a low dose and topically targeted, minimizing systemic absorption. Patients should avoid application to broken or irritated skin. Scream Cream is for external use only.
Frequently Asked Questions
A: Flibanserin (Addyi) is an oral daily medication that acts on brain neurotransmitters (serotonin/dopamine) to increase desire over weeks of use. Scream Cream is a topical applied before sexual activity that works locally to increase blood flow and sensitivity. They address different aspects of sexual function — central desire vs. peripheral arousal — and can potentially be used together if appropriate.
A: Yes. Scream Cream is a compounded prescription medication that must be prescribed by a licensed provider. The formulation is customized by a compounding pharmacy. Over-the-counter "arousal creams" typically lack the active pharmaceutical ingredients found in prescription Scream Cream.
A: Yes. Many women use Scream Cream in conjunction with systemic HRT (estradiol, progesterone, or testosterone). Systemic hormones address overall hormonal balance, while Scream Cream provides targeted, on-demand enhancement of sexual arousal and sensitivity. Your provider will ensure your complete protocol is coordinated.