Progesterone
60-day supply.
Prescription progesterone is one progestogen option used in some menopause hormone therapy regimens. When systemic estrogen is prescribed and the uterus is present, an appropriate progestogen is generally added to reduce endometrial-cancer risk. The exact product and schedule require individual review.
Interested in Progesterone?
Our medical team will evaluate if this medication is right for you during your consultation.
Dosage & Administration
Typically prescribed in capsule form, 25mg to 200mg, usually taken at night due to its calming/sedative effects. Exact dosing is highly individualized based on your labs, symptoms, and whether you still have a uterus (uterine protection requires adequate progesterone dosing).
Important: Like any prescribed medication, dosing varies from person to person. Always follow the dosage prescribed by your healthcare provider. Optimize 360 personalizes every protocol based on your labs, symptoms, and goals.
Side Effects
- Drowsiness and Dizziness: The most distinct side effect — often described as a "warm, sleepy feeling." This is why it's taken at bedtime.
- Headaches: Mild, particularly during dosage changes.
- Bloating: Some women experience mild water retention.
- Mood Changes: Adjusting progesterone is extremely personalized. Some women need higher doses for mood stability, others need lower.
Why Choose Optimize 360 for Progesterone
- Prescribed and monitored by Dr. Steve Farmer — 30+ years in hormone medicine
- Comprehensive lab work before prescribing — we never guess
- Sourced from licensed U.S. compounding pharmacies
- Transparent pricing — the price above is what you pay, no hidden fees
- Telehealth available nationwide — medications shipped to your door
- Unlimited messaging with your provider throughout treatment
Get Started Today
No memberships. No referral needed. Schedule your consultation and we'll take it from there.
Related
How Progesterone Works
Progesterone is a hormone produced by the body; prescription oral progesterone is one FDA-approved hormone therapy option. In some menopause regimens, appropriately prescribed progesterone may be used when systemic estrogen is given and the uterus is present to reduce endometrial-cancer risk. Read why a progestogen may be used with systemic estrogen and how uterus status changes that decision. The exact product and schedule require individual review.
Role in Menopause Hormone Therapy
When systemic estrogen is prescribed and the uterus is present, a clinician generally adds an appropriate progestogen to reduce estrogen-driven thickening of the uterine lining and the associated risk of endometrial cancer. Progesterone is one option; individual progestins are distinct medicines. The choice should be based on the prescribed estrogen, uterus status, health history, side effects, and product-specific evidence.
Who Is a Good Candidate?
A clinician may consider progesterone as part of a combined menopause hormone therapy regimen when systemic estrogen is prescribed and the uterus is present. People who have had a hysterectomy usually do not need a progestogen for uterine protection. A separate clinical reason should not be assumed from sleep, anxiety, or mood symptoms alone.
What to Expect: Treatment Timeline
Follow the exact schedule on the prescription. Combined regimens may be continuous or cyclic, and the appropriate follow-up depends on the medication, bleeding pattern, side effects, treatment goal, and health history. Do not change the amount, timing, or product based on a generic online timeline.
Side Effects & Safety
Possible effects depend on the exact product and regimen. ACOG lists spotting or bleeding, temporary breast soreness, bloating, and headaches among possible effects of hormone therapy. Report significant or unexpected symptoms and ask which bleeding changes require prompt or urgent assessment.
Frequently Asked Questions
A: No. Progesterone and individual progestins are distinct medicines. “Progestogen” is the umbrella term for both. Do not substitute products without prescriber direction.
A: Usually not for uterine protection, because the uterus is absent. A clinician may have another reason for prescribing it, and the surgery type should be confirmed before changing an existing plan.
A: Follow the exact written instructions for the prescribed product and regimen. If a dose is missed or the instructions are unclear, contact the prescriber or pharmacist rather than improvising.
Also Available